Researchers at WMG (formerly Warwick Manufacturing Group) at the University of Warwick in Coventry, UK, have developed a method to produce synthetic bone by borrowing techniques normally used to make catalytic converters for automobiles. Using state-of-the-art extrusion of the implant material through a mold, the scientists produced a three-dimensional honeycomb texture that contains uniform pores. Surgeons can sculpt this material to match a bone defect precisely. Following implantation, bone cells migrate into the implant and begin to form new bone. “We worked with a Japanese company which manufactures catalytic converters and used their facility to produce samples which we could test in the laboratory,” explains WMG researcher Kajal Mallick. “We found that we were able to use calcium phosphates — a family of bioceramics that are routinely used in bone implant operations — but by using this technique we were able to improve significantly both the strength and porosity of the implant.” The material’s increased strength could enable it to replace non-degradable materials such as titanium or steel in spinal surgery and in hip and knee revisions. The technique creates “nearly an ideal scaffold structure for efficient blood flow and formation of new bone cells,” Mallick adds. The researchers are working with Warwick Ventures, the university’s TTO, to seek a commercialization partner. Go to: ScienceDaily

Posted December 10th, 2008 under Innovation of the Week, Tech Transfer

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