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innovations available for license from research institutions worldwide
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July,
2009 -- Selected submissions this week: |
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Technology Summary: We have developed a unique and novel family of peptide nanostructures that are based on aromatic homo-dipeptides. This includes peptide nanotubes, nanospheres, and hydrogels with nano-scale order. It has also been demonstrated that these peptide nanotubes could serve as a mold for the fabrication of metals and building blocks of a novel electrochemical platform. Furthermore, the peptide tubes were demonstrated to have very strong mechanical rigidity with Young modulus of about 19 GPa. Click here for details >>
Name of Intellectual Property: Reconstituted fluorescent proteins for combinatorial marking of cells and cell structures Technology Summary: Green Fluorescent Protein (GFP) and its derivatives are used as reporters because they readily form active fusion proteins, can be safely expressed in cells and are easily visualized by standard microscopic techniques. This invention details the use of a “split” GFP, where the original GFP molecule is expressed as two separate polypeptides. When brought into close proximity, the polypeptides fold together, reconstituting the original protein and its fluorescent properties. Click here for details >>
Technology Summary: Dr. Karpen and his team have developed a novel research tool to detect activity of the cellular signaling molecule cAMP. They genetically engineered cyclic nucleotide-gated ion channels (CNGs) that are 2-20 fold more sensitive to activation by cAMP. Once activated, CNG channels allow positively charged calcium ions (Ca2+) to flow into the cell. This Ca2+ influx can either be recorded as an electrical current or imaged with fluorescent dyes. Click here for details >> |
ABOUT
HOT I.P. |
Hot I.P. is a regular e-bulletin presenting the best available technologies from universities and research institutions around the world. All submissions are judged as top-echelon, vetted innovations by the submitting organizations, and then are reviewed for quality, novelty, and likely market acceptance by Hot I.P.'s editorial staff prior to acceptance for publication. Each item links to a brief description of the technology, its inventor, patent status, and the business opportunity it represents, along with key contact information. Submit your group's nominee I.P. Please limit to one item submission per institution, per month. Click here for submission instructions. Why Hot I.P.? Unlike the currently existing IP databases and listing services, rather than residing on a website that users must visit and search within to find IP of interest, the Hot I.P. service actively sends these innovations out to our database of nearly 200,000. These include research commercialization professionals, investors, attorneys, corporate IP managers, consultants, economic development officials, and research administrators worldwide. In addition, we ensure the quality of the IP presented by accepting submissions only from leaders of university TTOs and other research institutions, who vouch for its novelty and market potential and select only from the top level of their IP portfolios. For complete details on this unique, low-cost but high-reach service, Click Here. |
Ramot
at Tel Aviv University, Ltd.
Columbia
University